Can eye color change with age or health conditions?

December 15, 2025 · caitlin

Eye color can change over time due to various factors, including age and certain health conditions. While significant changes are rare, subtle shifts may occur due to genetic, environmental, and medical influences.

What Causes Eye Color Changes?

Can Age Affect Eye Color?

Eye color can change subtly as people age. In infants, eye color often changes as melanin develops in the iris. Babies are typically born with blue or gray eyes, which may darken as they grow older. This change usually stabilizes by age three. In adults, eye color changes are less common but can occur due to the natural aging process. For example, the iris may lose pigment, leading to lighter eye color in older adults.

How Do Health Conditions Influence Eye Color?

Certain health conditions can cause changes in eye color, although these instances are relatively rare. Conditions that may affect eye color include:

  • Horner’s Syndrome: This neurological condition can cause one eye to appear lighter due to a lack of nerve supply to the iris.
  • Fuchs’ Heterochromic Iridocyclitis: This inflammatory eye condition can lead to a lighter-colored iris.
  • Pigmentary Glaucoma: A type of glaucoma that can cause pigment dispersion, potentially altering eye color.
  • Waardenburg Syndrome: A genetic disorder that can result in different colored eyes or changes in eye color.

Can Medications or Surgery Change Eye Color?

Certain medications, particularly those used to treat glaucoma, can cause changes in eye color. Prostaglandin analogs may increase melanin in the iris, leading to darker eyes over time. Additionally, surgical procedures involving the eye may occasionally affect eye color, although this is not common.

How Do Genetics Play a Role in Eye Color?

What Determines Eye Color?

Eye color is primarily determined by genetics, involving multiple genes that influence the amount and distribution of melanin in the iris. The OCA2 and HERC2 genes on chromosome 15 play significant roles in determining eye color. Variations in these genes can result in a spectrum of eye colors, from blue to brown.

Can Genetic Mutations Cause Eye Color Changes?

Genetic mutations can lead to changes in eye color, though these are usually present from birth rather than developing over time. For example, heterochromia, a condition where an individual has two different colored eyes, can be caused by genetic mutations.

People Also Ask

Can Stress or Emotions Change Your Eye Color?

Stress and emotions do not directly change eye color. However, pupil size can change with emotions, which might make the eyes appear different in color due to varying light reflections.

Is It Possible to Change Eye Color Naturally?

There is no natural method to permanently change eye color. While some believe diet or supplements can alter eye color, there is no scientific evidence to support these claims.

Are There Safe Methods to Change Eye Color?

Colored contact lenses are the safest and most effective way to change eye color temporarily. These lenses come in various shades and can be used for cosmetic purposes. It is crucial to use lenses prescribed by an eye care professional to avoid eye health issues.

Can Eye Color Indicate Health Problems?

In some cases, changes in eye color can indicate underlying health issues, such as Horner’s syndrome or pigmentary glaucoma. If you notice a sudden or significant change in your eye color, it is advisable to consult an eye care professional.

How Common Are Eye Color Changes?

Eye color changes are relatively uncommon in adults. Most people will retain their eye color throughout their lives, with only minor variations due to lighting or aging.

Summary

Eye color changes can occur due to various factors, including age, health conditions, and genetics. While significant changes are rare, subtle shifts are possible, particularly in infants and older adults. If you notice any unusual changes in your eye color, it is important to consult an eye care professional to rule out any underlying health conditions. For those interested in changing their eye color for cosmetic reasons, colored contact lenses offer a safe and temporary solution.

For further reading, consider exploring topics such as "How Genetics Influence Eye Color" and "The Impact of Aging on Vision."

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