Can heterochromia develop later in life?

December 20, 2025 · caitlin

Can heterochromia develop later in life? Yes, heterochromia can develop later in life due to various factors such as injury, disease, or medication. While many people are born with heterochromia, known as congenital heterochromia, it can also manifest in adulthood, a condition referred to as acquired heterochromia.

What is Heterochromia?

Heterochromia is a condition characterized by differences in the coloration of the eyes. This can result in one iris being a different color from the other (complete heterochromia) or parts of one iris being different colors (partial or sectoral heterochromia). The condition can be congenital, present from birth, or acquired later in life.

Causes of Acquired Heterochromia

Can Injury Cause Heterochromia?

Yes, an eye injury can lead to heterochromia. Trauma can alter the pigmentation in the iris, resulting in a change of color. This might happen if the injury affects the melanin production or distribution in the eye.

How Do Diseases Affect Eye Color?

Certain diseases can cause heterochromia. Conditions like Horner’s syndrome, glaucoma, and Fuchs’ heterochromic iridocyclitis can influence eye color. These diseases may affect the eye’s structure or pigmentation, leading to changes in color.

Do Medications Influence Eye Color?

Some medications, particularly those for glaucoma, can cause heterochromia. Prostaglandin analogs, used in glaucoma treatment, may darken the iris over time, leading to a noticeable change in eye color.

Types of Heterochromia

Heterochromia is categorized into three main types:

  • Complete Heterochromia: One iris is a completely different color from the other.
  • Sectoral Heterochromia: Part of one iris is a different color from the rest.
  • Central Heterochromia: The inner ring of the iris is a different color than the outer ring.

Is Acquired Heterochromia Permanent?

The permanency of acquired heterochromia depends on its cause. If heterochromia results from medication or disease, it might be reversible if the underlying issue is addressed. However, changes due to injury are often permanent.

Examples of Acquired Heterochromia

  • David Bowie: Although often cited as an example of heterochromia, Bowie actually had anisocoria, a condition where one pupil is larger than the other, giving the appearance of different eye colors.
  • Mila Kunis: The actress reportedly developed heterochromia following an eye infection.

People Also Ask

Can Stress Cause Heterochromia?

Stress alone is unlikely to cause heterochromia. However, stress-related conditions or injuries might indirectly contribute to changes in eye color.

Is Heterochromia Dangerous?

Heterochromia itself is generally not dangerous. However, if it develops suddenly, it could indicate an underlying medical condition that requires attention.

How Common is Heterochromia?

Heterochromia is relatively rare, affecting less than 1% of the population. Acquired heterochromia is even less common than congenital heterochromia.

Can Heterochromia Affect Vision?

Heterochromia typically does not affect vision. However, if it is associated with an underlying condition, that condition might impact vision.

How is Heterochromia Diagnosed?

Heterochromia is diagnosed through an eye examination. An ophthalmologist may conduct tests to determine if there is an underlying cause for the color change.

Conclusion

Heterochromia can indeed develop later in life, often due to injury, disease, or medication. Understanding the underlying causes is crucial for appropriate management. If you notice changes in your eye color, it is advisable to consult an eye care professional to rule out any serious conditions. For further reading, explore topics such as eye health and common eye conditions to gain more insights into ocular health.

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