What causes someone to have different colored eyes?

December 19, 2025 · caitlin

What causes someone to have different colored eyes? This intriguing condition, known as heterochromia, occurs due to variations in the concentration and distribution of melanin, the pigment responsible for eye color. Heterochromia can be present at birth or develop later in life due to genetic factors, injury, or disease.

What Are the Types of Heterochromia?

Heterochromia is categorized into three main types, each with distinct characteristics:

  • Complete heterochromia: One iris is a completely different color from the other.
  • Sectoral (or partial) heterochromia: A single iris contains two or more colors.
  • Central heterochromia: The iris has a different color around the pupil compared to the outer part.

What Causes Heterochromia?

Genetic Factors

Genetic heterochromia is often inherited and is usually benign. It can be a standalone trait or part of a genetic syndrome, such as Waardenburg syndrome or Sturge-Weber syndrome. These conditions may have other associated symptoms, but heterochromia itself typically does not affect vision.

Injury or Trauma

Eye injuries can lead to heterochromia if they affect melanin distribution. For example, a blunt trauma might cause bleeding in the eye, altering its color.

Disease or Medical Conditions

Certain diseases can result in heterochromia, including:

  • Glaucoma: Treatment or progression of this eye condition can change eye color.
  • Fuchs’ heterochromic iridocyclitis: This rare inflammatory condition affects the iris and can cause color changes.
  • Horner’s syndrome: This neurological disorder can lead to changes in eye coloration.

Medication

Some medications, particularly those used to treat glaucoma, can cause changes in eye color over time. Prolonged use of certain eye drops may increase melanin in the iris, leading to darker eye color.

Can Heterochromia Affect Vision?

Heterochromia itself does not typically affect vision. However, if it’s a symptom of an underlying condition, that condition might impact vision. It’s essential to consult an eye specialist if you notice any sudden changes in eye color to rule out potential health issues.

Examples of Heterochromia in Celebrities

Numerous public figures have heterochromia, bringing attention to this unique trait:

  • David Bowie: Although often thought to have heterochromia, Bowie actually had anisocoria, where one pupil is larger than the other, giving the appearance of different colored eyes.
  • Kate Bosworth: Known for her striking sectoral heterochromia, with one blue eye and one hazel eye.
  • Mila Kunis: She has partial heterochromia, with one eye being a different shade than the other.

People Also Ask

What is the most common type of heterochromia?

The most common type is sectoral heterochromia, where part of one iris is a different color than the rest. It’s often less noticeable than complete heterochromia and can be a subtle feature.

Can heterochromia develop later in life?

Yes, heterochromia can develop later in life due to trauma, disease, or medication. If you notice a sudden change in eye color, it’s advisable to seek medical attention to determine the cause.

Is heterochromia hereditary?

Heterochromia can be hereditary, especially in cases with no associated medical conditions. It can also be part of genetic syndromes, which may have other health implications.

Does heterochromia affect animals?

Yes, heterochromia occurs in animals, particularly in certain dog and cat breeds. For example, Siberian Huskies and Australian Shepherds often have heterochromia, which is considered normal and does not affect their health.

How is heterochromia diagnosed?

Diagnosis typically involves a comprehensive eye exam. An eye specialist will assess the eyes and may conduct further tests if an underlying condition is suspected.

Conclusion

Heterochromia, while visually striking, is often a benign trait caused by genetic factors, injuries, or medical conditions. Understanding its types and causes can help you appreciate its uniqueness and recognize when to seek medical advice. If you’re interested in learning more about eye health, consider exploring topics like eye anatomy or common eye conditions for a deeper understanding.

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