What determines a person’s eye color?

November 23, 2025 · caitlin

A person’s eye color is determined by the pigmentation of the iris and the way light scatters within it. The primary factors influencing eye color include genetics, the amount of melanin present, and the structure of the iris. Understanding these elements can help explain the wide variety of eye colors observed across different populations.

What Role Does Genetics Play in Eye Color?

Genetics is the most significant factor in determining eye color. The color of a person’s eyes is primarily inherited, with multiple genes contributing to the outcome. The two main genes involved are OCA2 and HERC2, located on chromosome 15. These genes influence the production and distribution of melanin, the pigment responsible for the color of the eyes, skin, and hair.

  • OCA2 Gene: This gene controls the amount of melanin stored in the iris. Variations in this gene can lead to a range of eye colors from blue to brown.
  • HERC2 Gene: This gene regulates the expression of the OCA2 gene. A specific region within HERC2 can turn the OCA2 gene on or off, affecting melanin production and, consequently, eye color.

How Does Melanin Affect Eye Color?

Melanin is the primary pigment that determines eye color. The amount and type of melanin in the iris dictate whether eyes appear blue, green, hazel, or brown.

  • Brown Eyes: High levels of melanin result in brown eyes, the most common eye color worldwide.
  • Blue Eyes: Low melanin levels lead to blue eyes, where the lack of pigment causes more light scattering, creating a blue appearance.
  • Green and Hazel Eyes: Intermediate levels of melanin and the presence of other pigments can lead to green or hazel eyes.

The distribution and concentration of melanin can vary, leading to subtle differences in individual eye color.

What Other Factors Influence Eye Color?

While genetics and melanin are the primary determinants, other factors can influence eye color:

  • Age: Eye color can change over a person’s lifetime. Many babies are born with blue or gray eyes that darken as melanin production increases with age.
  • Lighting and Environment: The perception of eye color can change depending on lighting conditions. For example, eyes may appear lighter or darker in different lighting.
  • Health Conditions: Certain conditions, such as Horner’s syndrome or Fuchs’ heterochromic iridocyclitis, can cause changes in eye color.

Can Eye Color Change Over Time?

Yes, eye color can change over time due to several factors:

  • Natural Changes: As mentioned, many infants experience changes in eye color as they grow older. This is usually due to increased melanin production.
  • Medical Conditions: Some diseases or medications can alter eye color. For instance, glaucoma medications may increase iris pigmentation.
  • Injury or Surgery: Trauma or surgical procedures can sometimes lead to changes in eye color.

People Also Ask

What Determines Eye Color Genetics?

Eye color genetics is determined by multiple genes, primarily OCA2 and HERC2, which influence melanin production. Variations and interactions among these genes result in the diverse range of eye colors seen across individuals.

Can Two Blue-Eyed Parents Have a Brown-Eyed Child?

While rare, it is possible for two blue-eyed parents to have a brown-eyed child due to the complex nature of eye color genetics. Recessive genes carried by the parents can sometimes lead to unexpected outcomes.

Why Do Some People Have Two Different Colored Eyes?

Having two different colored eyes, known as heterochromia, can be genetic or caused by injury, disease, or certain medications. It results from variations in melanin distribution between the eyes.

Is It Possible to Change Eye Color Naturally?

Natural changes in eye color typically occur in infancy or due to aging. There are no proven methods to change eye color deliberately without medical intervention.

How Common Are Green Eyes?

Green eyes are one of the rarest eye colors, found in only about 2% of the global population. They result from a combination of low melanin levels and the presence of a yellowish pigment called lipochrome.

Conclusion

In summary, a person’s eye color is largely determined by genetics, particularly the interaction of the OCA2 and HERC2 genes, which influence melanin production. While eye color is predominantly stable, it can change due to age, lighting, or health conditions. Understanding the factors that determine eye color can provide insight into the fascinating diversity of human appearance. For more on genetic traits and variations, explore related topics such as hair color genetics and skin pigmentation.

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